In this webinar, experts provide an overview of causal inference, along with step-by-step guidance to designing these studies using real-world healthcare data.
Causal inference is used to answer cause and effect research questions and yield estimates of effect. Causal study design considerations and statistical methods address the effects of confounding variables and other potential biases and allow researchers to answer questions such as, “Does treatment A produce better patient outcomes compared to Treatment B?”
Causal study interpretations have traditionally been restricted to randomized controlled trials; however, causal inference applied to observational healthcare data is growing in importance, driven by the need for generalizable and rapidly delivered real-world evidence to inform regulatory, payer, and patient/provider decision making. The application of causal inference methods leads to stronger and more powerful evidence. When these techniques are applied to observational data, the results generated are both from and for the real world.
Along with an overview of causal inference and guidance to designing these studies using real-world healthcare data, presenters walk through several real-world case studies, including the PCORI-funded BESTMED study and a collaborative study with a prominent pharmacy payer.
Key Topics Include:
- The underlying need for explicit consideration of causal study design principles
- How to design causal inference studies using real-world data
- Real-world case study examples and success stories
Director of Informatics Research
Division of Endocrinology
Brigham and Women's Hospital
Associate Research Director