Understanding the Power of Platform Trials

A recent Cytel blog post details the benefits of one category of the Master Protocol termed the platform trial, typically used to compare numerous treatments or combinations thereof across diverse patient populations. An on-demand Cytel webinar contrasts different approaches to platform trials, including one recent example assessing the cost-effectiveness of the antidepressant fluvoxamine in patients with COVID-19.

“Unlike traditional clinical trials, in platform studies not all interventions are included or even known at the beginning. This approach allows us to answer the question of what the best treatment option is for a given disease in a single perpetual trial by allowing interventions to enter and leave at different time points.” Read more here.

(Source: Mansha Sachdev, Cytel, 10/29/21)