Real-World Data Study Characterizes Long-Term Outcomes in Patients Hospitalized with COVID-19

June 13, 2023

COVID-19 has long-term repercussions for patients who recover, but these effects are poorly characterized. In a newly published study in The Lancet, researchers examined the health outcomes of patients 6 months after being discharged from a hospital in Wuhan, China for COVID-19. The study, which examined data from 2469 patients, found that many patients experienced muscle weakness, sleep disturbances, or mental health issues.

According to the authors, “To our knowledge, this is the largest cohort study with the longest follow-up duration assessing the health consequences of adult patients discharged from hospital recovering from COVID-19. We found that at 6 months after symptom onset, most patients endorsed at least one symptom, particularly fatigue or muscle weakness, sleep difficulties, and anxiety or depression. More severely ill patients had increased prevalence of pulmonary diffusion abnormality, fatigue or muscle weakness, and anxiety or depression. The seropositivity and titres of the neutralising antibodies were significantly lower than at acute phase.”

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