New Cytel Blog on Causal Inference and RWD in Decision Making

A new Cytel blog post discusses using real world data (RWD) to bypass phase IV clinical trials. In contrast to randomized clinical trials (RCTs), target trials using RWD allow researchers to address causal questions and inform pharmaceutical decision-making processes.

“We try to emulate the RCT using real world data. A Target trial is the hypothetical randomized trial that we would like to conduct to answer a causal question. Any causal inference of observational data that we conduct can be viewed as an attempt to emulate some target trial.” Read more here.

(Source: Mansha Sachdev, Cytel, 8/20/21)