Over the past decade, a new trend began to emerge, changing the way that clinical trials are conducted. Where-as placebo-controlled randomized trials control trials remain the gold standard, in some situations synthetic control arms can be used instead. Synthetic control arms leverage real world data from various sources or evaluations of historical clinical data to demonstrate the positive effects of a new therapy or treatment, without the need to use a placebo or standard of care as a control.
This method saves sponsors time and money and can be particularly valuable for oncology and rare disease trials faced with recruitment challenges and ethical issues.
Join Kristian Thorlund, SVP, Real World Analytics at Cytel, for a complimentary webinar as he introduces synthetic control arms and discusses the validity of data, results and interpretations. In addition, there is also a FREE eBook ‘Demystifying synthetic control arms’ which you can download detailing common strategies, challenges and use cases.